Rinse Karel Weersma

This study identifies 619 IBD risk signals, resolves 81 high-confidence variants, and prioritizes 664 candidate effector genes using GWAS, eQTL, and exome sequencing.

This study uses exome and genome sequencing to identify 68 genes directly associated with inflammatory bowel disease, providing clearer genetic insights and therapeutic targets.

The paper compiles 2,658 Desulfovibrio genomes from 90 diseases and 32 countries to identify species-specific functional traits linked to inflammatory diseases.

The paper identifies a novel subspecies of Bifidobacterium longum, BL. nexti, in infant gut microbiomes, showing its association with formula feeding and vertical transmission.

This study analyzes the gut microbiome of treated coeliac disease patients at strain level, revealing increased interindividual variation and specific microbial associations.

The paper identifies that impaired COPII vesicle enlargement due to reduced TANGO1 expression contributes to ER stress in IBD by affecting mucin-2 secretion.

The paper examines gut microbiome changes across different cardiovascular risk levels and in STEMI patients, identifying microbial species and pathways associated with cardiovascular risk and disease.

The paper identifies host genetic loci associated with gut microbiome composition and function in a large cohort, finding significant associations near LCT and ABO genes.

This study identifies shared and ethnicity-specific HLA associations with ulcerative colitis through trans-ethnic analysis of diverse populations.