Author

Tek-Hyung Lee

ORCID 0000-0002-8299-0401Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Chenrui XuiD· 1 shared Longfei Cong· 1 shared Per Jr GreiseniD· 1 shared Roger ShekiD· 1 shared Trang Nguyen· 1 shared Yi LiiD· 1 shared Yi ZhouiD· 1 shared Yifan LiiD· 1 shared

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2025-2025 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBioengineering

Chenrui XuORCID

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1 paper

Recent·Most cited

De Novo Computational Design of VHH Nanobodies Against LGR5

Chenrui Xu, Yifan Li, Trang Nguyen, Yi Zhou, Longfei Cong, Tek-Hyung Lee, Yuxiang Lang, Roger Shek, Yi Li, Per Jr Greisen

This paper presents a computational pipeline for designing VHH nanobodies against LGR5 without structural templates, resulting in high-affinity, stable binders validated by cryo-EM.

bioRxiv · Dec 5, 2025 · PreprintBioengineering