BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Glycosaminoglycans act as activators of peptidylarginine deiminase 4
Grzegorz P. Bereta, Ewa Bielecka, Karolina Marzec…·Tomasz Kantyka
This study identifies glycosaminoglycans as activators of PAD4, showing they enhance Ca2+ affinity and induce NETosis, with implications for rheumatoid arthritis.
6 citations