Author

George Russel Wendt

The University of Texas Southwestern Medical CenterORCID 0000-0002-8302-079XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

James J. CollinsiD· 3 shared Chih-Wei Fan· 1 shared David J. MangelsdorfiD· 1 shared H Eric Xu· 1 shared Jeffrey G. McDonaldiD· 1 shared Lauren G. ZachariasiD· 1 shared Lu ZhaoiD· 1 shared Melissa Goellner MitchumiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMicrobiology

James J. CollinsORCID

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3 papers

Recent·Most cited

Conservation of Nuclear Receptor DAF-12 with Evidence for Ligand Diversification in Plant-Parasitic Nematodes

Yanjie Liu, Chih-Wei Fan, Zhu Wang, George Russel Wendt, Lauren G. Zacharias, Jeffrey G. McDonald, Yunhai Li, Shi-yi Shen, H Eric Xu, James J. Collins, Steven A. Kliewer, Melissa Goellner Mitchum, David J. Mangelsdorf, Thomas P. Mathews

The paper investigates DAF-12 receptor ligand responsiveness in plant-parasitic nematodes and finds structural diversity in ligand recognition.

bioRxiv · Sep 7, 2026 · PreprintMolecular Biology

Horizontal gene transfer of a functional cki homolog in the human pathogen Schistosoma mansoni

George Russel Wendt, James J. Collins

The paper identifies a functional cki homolog in Schistosoma mansoni, showing it acts as a tumor suppressor and suggests its origin via horizontal gene transfer from free-living ancestors.

Science Advances · Dec 10, 2025Peer-reviewedMicrobiology

A Kruppel-like factor establishes cellular heterogeneity during schistosome tegumental maintenance

Lu Zhao, George Russel Wendt, James J. Collins

The paper identifies klf4's role in maintaining tegumental cell heterogeneity in schistosomes through bulk and single-cell RNAseq, showing its necessity for lineage maintenance and molecular balance.

PLoS Pathogens · Mar 28, 2025Peer-reviewedMicrobiology