Pharmacology & ToxicologybioRxivPreprint
High-throughput drug screening for inhibition of influenza A virus infection based on human SIRT1 promoter and Genipin suppressing influenza A virus by activation of AMPK-SIRT1-PGC-1α signaling pathway
Jinghan Ye, Dekun Liu, Qianwen Wang, Jianping Dai
This study identifies Genipin and its derivatives as inhibitors of influenza A virus replication by activating the AMPK-SIRT1-PGC-1α signaling pathway and altering metabolic reprogramming.
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