Jiali Han

This paper identifies 116 risk loci for melanoma through GWAS, links susceptibility to immunity and Wnt signaling, and develops a PRS improving risk prediction.

The paper identifies a novel cancer susceptibility mutation in hfBCC patients by analyzing skin mutagenesis and its association with BCC and prostate cancer.

This study conducts a large-scale GWAS meta-analysis of nevus count, identifying 29 new loci and highlighting immune-related pathways relevant to melanoma risk.

This study identifies 48 genetic variants associated with handedness using a large GWAS, highlighting polygenic nature and genetic links to neuropsychiatric traits.

This paper identifies novel pleiotropic risk loci for melanoma and nevus density, implicating multiple biological pathways and gene expression under MITF regulation.

This paper shows that explicitly modeling genetic ancestry improves polygenic risk scores and BLUP prediction accuracy for complex traits by reducing ancestry-related biases in SNP effect estimation.