Author
QIMR Berghofer Medical Research InstituteORCID 0000-0003-4760-1033Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
6 papers
Recent·Most cited
G J M Shanika R Jayasinghe, Jianxin Shi, Rohit Thakur…·Nhan Do
This paper identifies 116 risk loci for melanoma through GWAS, links susceptibility to immunity and Wnt signaling, and develops a PRS improving risk prediction.
Peter A. Johansson, Kelly M. Brooks, Jane M. Palmer…·Antonia L. Pritchard
The paper identifies a large distant deletion in DMRTA1 upstream of CDKN2A that predisposes to melanoma by disrupting regulatory sequences and reducing p16 expression.
G J M Shanika R Jayasinghe, Gu Zhu, Nirmala Pandeya…·Matthew H. Law
This study conducts a large-scale GWAS meta-analysis of nevus count, identifying 29 new loci and highlighting immune-related pathways relevant to melanoma risk.
Kevin M. Brown, Mai Xu, Michael R. Sargen…·Maria Teresa Landi
The paper identifies a novel NRAS variant in a melanoma-prone family and shows it impairs MAPK/AKT signaling while enhancing PI3K signaling.
David L. Duffy, Gu Zhu, Xin Li…·Nicholas Orr
This paper identifies novel pleiotropic risk loci for melanoma and nevus density, implicating multiple biological pathways and gene expression under MITF regulation.