Recovery of a minor cryo-EM particle population reveals conformational equilibria linking cofactor loading, turnover, and reactivation in methionine synthase
Haoyue Wang, Maxwell B. Watkins, Pasa Suksmith, Nozomi Ando
The paper reanalyzes a cryo-EM dataset using advanced methods to uncover a minor reactivation-state structure of methionine synthase, revealing conformational changes during cofactor turnover.
Biochemistry · Oct 27, 2026Peer-reviewedBiochemistry