Nozomi Ando

The paper reanalyzes a cryo-EM dataset using advanced methods to uncover a minor reactivation-state structure of methionine synthase, revealing conformational changes during cofactor turnover.

This study reveals that E. coli ATCase uses allosteric breathing to tune cooperativity between active sites, with nucleotides acting as symmetric regulators.

This study uses cryo-EM and deep learning to analyze conformational changes in ribonucleotide reductase during turnover, revealing dynamic asymmetry and transient states essential for catalysis.

The paper introduces mdx2, a Python toolkit for processing diffuse scattering data from macromolecular crystals, demonstrating multi-crystal scaling and merging workflows with a cubic insulin dataset.

The paper performs a comprehensive phylogenetic analysis of ribonucleotide reductase (RNR) family to identify an ancestral clade and trace evolutionary diversification through insertions and extensions.