Maxwell B. Watkins

The paper reanalyzes a cryo-EM dataset using advanced methods to uncover a minor reactivation-state structure of methionine synthase, revealing conformational changes during cofactor turnover.

This study resolves heterogeneity in targeted lipid nanoparticles (tLNPs) using biophysical methods, showing that subpopulation structure, not bulk properties, determines targeted RNA delivery.

The paper investigates how intramolecular interactions between folded and disordered regions of ubiquilin proteins influence their structure and function across different species.

The paper identifies a coiled-coil linker mechanism in RsbU that activates the General Stress Response in bacteria by transducing signals from sensor domains.