Transcriptomic Stratification of Late-Onset Alzheimer’s Cases Reveals Novel Genetic Modifiers of Disease Pathology
Nikhil Milind, Christoph Preuß, Annat Haber, Guruprasad Ananda, Shubhabrata Mukherjee, John Cai, Sarah M. Shapley, Anna L. Tyler, Benjamin A. Logsdon, Paul K. Crane, Gregory W. Carter
This study identifies novel genetic modifiers of late-onset Alzheimer's disease by stratifying patients into molecular subtypes using transcriptomic data and whole genome sequencing.
PLoS Genetics · Jun 3, 2020Peer-reviewedSystems Biology