Alexander R. Mikesell

This study shows that keratinocytes contribute to mechanical and cold hypersensitivity after traumatic nerve injury and that pannexin-1 activation is critical for this effect.

The paper shows that keratinocyte Piezo1 contributes to paclitaxel-induced mechanical hypersensitivity by sensitizing keratinocytes to mechanical stimulation.

This study identifies TRPC5 as a mediator of inflammatory mechanical pain using knockout mice and pharmacological inhibitors, showing its role in pain behaviors induced by lysophosphatidylcholine.