Author

Zhu‐Xu Zhang

Western UniversityORCID 0000-0002-8335-3738Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Aaron R. HaigiD· 1 shared Aditya N. BrahmbhattiD· 1 shared Anthony M. JevnikariD· 1 shared Bianca GarlisiiD· 1 shared Brooke A. Morris· 1 shared Caroline Aitken· 1 shared Christopher G. R. PerryiD· 1 shared Fasih Ahmad RahmaniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Aaron R. HaigORCID

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2 papers

Recent·Most cited

The mitochondrial-targeted antioxidant SkQ1 prevents mitochondrial-linked apoptosis but not necroptosis or skeletal muscle atrophy in ovarian cancer

Shahrzad Khajehzadehshoushtar, Luca J. Delfinis, Fasih Ahmad Rahman, Madison C. Garibotti, Shivam Gandhi, Aditya N. Brahmbhatt, Brooke A. Morris, Bianca Garlisi, Sylvia Lauks, Caroline Aitken, Leslie M. Ogilvie, Zhu‐Xu Zhang, Jeremy A. Simpson, Joe Quadrilatero, Jim Petrik, Christopher G. R. Perry

This paper investigates the role of mitochondrial ROS in skeletal muscle atrophy during ovarian cancer and finds that SkQ1 reduces mitochondrial-linked apoptosis but not necroptosis or atrophy.

The Journal of Physiology · Nov 2, 2025Peer-reviewedPhysiology

ADAR1 orchestrates the ZBP1-mediated PANoptosis and heart transplant rejection

Haitao Lü, Jifu Jiang, Xuyan Huang, Aaron R. Haig, Lakshman Gunaratman, Anthony M. Jevnikar, Zhu‐Xu Zhang

This study shows ADAR1 regulates ZBP1-RIPK3 complex activation to mediate PANoptosis in heart transplant rejection, with ZBP1 inhibition reducing graft injury and improving survival.

bioRxiv · Sep 5, 2024 · PreprintMolecular Biology