Systems BiologyPLoS Computational BiologyPeer-reviewed
Using Deep Learning to Decipher the Impact of Telomerase Promoter Mutations on the Morpholome
Andres J. Nevarez, Anusorn Mudla, Sabrina A. Diaz, Nan Hao
The paper investigates how telomerase promoter mutations affect melanoma cell morphology using isogenic cell lines and dual-color reporters, finding C250T mutations cause more pronounced morphological changes.
DOI 10.1371/journal.pcbi.1012271