Author

Yingjun Li

Huazhong Agricultural UniversityORCID 0000-0002-8339-2104Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

Nan PengiD· 2 shared Tao LiuiD· 2 shared Zhufeng ZhangiD· 2 shared Bo WuiD· 1 shared Guoquan HuiD· 1 shared Mingxiong HeiD· 1 shared Saifu Pan· 1 shared Xiaojie WangiD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersGenetics

Nan PengORCID

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2 papers

Recent·Most cited

Primed acquisition and microhomology-mediated end-joining cooperate to confer specific CRISPR immunity against invasive genetic elements

Xiaojie Wang, Bo Wu, Zhufeng Zhang, Tao Liu, Yingjun Li, Guoquan Hu, Mingxiong He, Nan Peng

This study shows that Zymomonas mobilis uses primed CRISPR acquisition for specific invader DNA uptake and microhomology-mediated end-joining for repairing DNA breaks caused by self-targeted spacers.

bioRxiv · Nov 6, 2019 · PreprintGenetics

Cas4 nucleases can effect specific integration of CRISPR spacers

Zhufeng Zhang, Saifu Pan, Tao Liu, Yingjun Li, Nan Peng

This study identifies Cas4 and Csa1 proteins as essential for specific CRISPR spacer acquisition, showing they recognize protospacer motifs and determine spacer length and orientation, with virus-encoded Cas4 proteins potentially inhibiting CRISPR-Cas interference.

Journal of Bacteriology · Mar 29, 2019Peer-reviewedMolecular Biology