Joseph H. McCarty

The Endothelial Cell-Expressed Prion Protein Prnd/Doppel Promotes Neovascularization and Long-term Recovery after Ischemic Stroke

This study shows that Prnd/Doppel in endothelial cells promotes vascular remodeling and long-term recovery after stroke, improving neuronal survival and reducing inflammation.

Single Cell Spatial Profiling Identifies Region-Specific Extracellular Matrix Adhesion and Signaling Networks in Glioblastoma

This study uses spatial transcriptomics to identify ECM expression patterns in GBM, revealing region-specific adhesion and signaling networks in the tumor microenvironment.

GlialCAM Cytoplasmic Signaling in Oligodendrocytes and Astrocytes is Essential for White Matter Homeostasis in the Brain

This study investigates the role of GlialCAM's cytoplasmic tail in white matter homeostasis using a mutant mouse model, revealing defects in ECM remodeling and glial activation.

Single Cell RNA Sequencing and Spatial Profiling Identify Mechanisms of Neonatal Brain Hemorrhage Development and Resolution

The paper uses single-cell RNA sequencing and spatial profiling to identify signaling networks involved in neonatal brain hemorrhage development and resolution in mice.