Author

Santiago A. Forero

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-8809-3656Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

John E. MoralesiD· 3 shared Joseph H. McCartyiD· 3 shared Ali Pirani· 2 shared Arpan DeiD· 2 shared Sumod Sebastian· 2 shared Zhihua CheniD· 2 shared Ali Mohammed PiraniiD· 1 shared Frederick F. LangiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCancer Biology

John E. MoralesORCID

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Author profile →

3 papers

Recent·Most cited

Single Cell Spatial Profiling Identifies Region-Specific Extracellular Matrix Adhesion and Signaling Networks in Glioblastoma

Arpan De, Santiago A. Forero, Ali Mohammed Pirani, John E. Morales, Marisol De La Fuente, Sumod Sebastian, Jason T. Huse, Leomar Y. Ballester, Jeffrey S. Weinberg, Frederick F. Lang, Kadir Caner Akdemir, Joseph H. McCarty

This study uses spatial transcriptomics to identify ECM expression patterns in GBM, revealing region-specific adhesion and signaling networks in the tumor microenvironment.

Communications Biology · Dec 9, 2025Peer-reviewedCancer Biology

GlialCAM Cytoplasmic Signaling in Oligodendrocytes and Astrocytes is Essential for White Matter Homeostasis in the Brain

Zahra Nassiri Toosi, Santiago A. Forero, Ali Pirani, Sumod Sebastian, Tao Wang, Zhihua Chen, Xiaofeng Zheng, John E. Morales, Joseph H. McCarty

This study investigates the role of GlialCAM's cytoplasmic tail in white matter homeostasis using a mutant mouse model, revealing defects in ECM remodeling and glial activation.

bioRxiv · Oct 3, 2025 · PreprintNeuroscience

Single Cell RNA Sequencing and Spatial Profiling Identify Mechanisms of Neonatal Brain Hemorrhage Development and Resolution

Santiago A. Forero, Zhihua Chen, Ali Pirani, Arpan De, Zachary Wise, John E. Morales, Joseph H. McCarty

The paper uses single-cell RNA sequencing and spatial profiling to identify signaling networks involved in neonatal brain hemorrhage development and resolution in mice.

bioRxiv · Jul 30, 2025 · PreprintDevelopmental Biology