Early-life stress exposure impacts the hippocampal synaptic proteome in a mouse model of Alzheimer's disease: age- and pathology-dependent effects on mitochondrial proteins
Janssen M. Kotah, Mandy S. J. Kater, Niek Brosens, Sylvie L. Lesuis, Roberta Tandari, Thomas M. Blok, Luca Marchetto, Ella Yusaf, Frank Koopmans, August Benjamin Smit, Paul John Lucassen, Harm J. Krugers, Mark H. G. Verheijen, Anikó Kőrösi
This study examines how early-life stress affects the synaptic proteome in Alzheimer's disease mouse models, revealing age- and pathology-dependent changes in mitochondrial and astrocytic proteins.
Alzheimer s & Dementia · Dec 6, 2023Peer-reviewedNeuroscience