Author

Daniel James

Paul Scherrer InstituteORCID 0000-0002-8348-6661Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Antonia FurreriD· 2 shared Camila BacellariD· 2 shared Christopher Jackson MilneiD· 2 shared Claudio CirelliiD· 2 shared Dardan Gashi· 2 shared Dmitry OzeroviD· 2 shared Florian DworkowskiiD· 2 shared Joerg StandfussiD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiophysics

Antonia FurrerORCID

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2 papers

Recent·Most cited

Covalent bond formation caught in a LOV photoreceptor

Bence Olasz, Guillaume Gotthard, Probal Nag, María González-Viegas, Sandra TM Mous, Anna Koczurowska, Philip J. M. Johnson, Tokushi Sato, Madan Kumar Shankar, Maximilian Wranik, Aleksandra Solecka, Diogo V. M. Melo, Ran Ke, Daniel James, Karol Nass, , Przemysław Nogły

This paper resolves the mechanism of covalent bond formation in a LOV photoreceptor using time-resolved crystallography and spectroscopy, revealing a water-mediated proton transfer that accelerates the reaction by fourteen orders of magnitude.

bioRxiv · Aug 6, 2026 · PreprintBiophysics

Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography

Maximilian Wranik, Tobias Weinert, Chavdar Slavov, Tiziana Masini, Antonia Furrer, Natacha Gaillard, Dario Gioia, Marco Jacopo Ferrarotti, Daniel James, Hannah Glover, Melissa Carrillo, Demet Kekilli, Robin Stipp, Petr Skopintsev, Steffen Brünle, , Jörg Standfuss

The paper captures the release of a photopharmacological drug from tubulin using time-resolved serial crystallography and shows how ligand release triggers conformational changes.

Nature Communications · Feb 17, 2023Peer-reviewedMolecular Biology