Author

Laura Merlini

University of GenevaORCID 0000-0002-8355-9541Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:proteomics· 1

Frequent Co-Authors

Sophie S. MartiniD· 3 shared Aiswarya Sajeevan· 1 shared Boris SieberiD· 1 shared Laetitia MichoniD· 1 shared Maelys BesomiiD· 1 shared Melvin Bérard· 1 shared Sajjita SahaiD· 1 shared Sushila Gordon-Lennox· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

Sophie S. MartinORCID

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3 papers

Recent·Most cited

High levels of Cdc42 GTPase underlie an all-or-none decision to fuse

Sajjita Saha, Aiswarya Sajeevan, Laura Merlini, Vincent Vincenzetti, Sophie S. Martin

This study shows that high Cdc42 levels are required for cell fusion in yeast, with distinct regulatory mechanisms compared to polarized growth.

PLoS Biology · Mar 19, 2026Peer-reviewedCell Biology

Negative feedback regulation of the hemi-arrestin MAPK scaffold Sms1 prevents untimely mating

Boris Sieber, Laura Merlini, W. Li, Maelys Besomi, Laetitia Michon, Sushila Gordon-Lennox, Sophie G. Martin

The paper identifies Sms1 as a novel MAPK scaffold in fission yeast that regulates mating by negative feedback through membrane translocation.

Nature Communications · Mar 17, 2026Peer-reviewedCell Biology

TORC1 reactivation by pheromone signaling revealed by phosphoproteomics of fission yeast sexual reproduction

Melvin Bérard, Laura Merlini, Sophie G. Martin

The paper uses phosphoproteomics to show that TORC1 is reactivated by pheromone signaling in fission yeast during sexual reproduction, supporting spore viability.

PLoS Biology · Dec 20, 2024Peer-reviewedCell Biology