This study examines the effects of prenatal alcohol and synthetic cannabinoid co-exposure on mouse offspring survival, physical development, and neurobehavioral outcomes, finding increased mortality and sex-specific behavioral impairments.

Drug and Alcohol Dependence Reports · Jul 2, 2025Peer-reviewedAnimal Behavior & Cognition

Reduced fetal cerebral blood flow following prenatal drug exposure predicts perinatal mortality.

Siara Kate Rouzer, Anirudh Sreeram, Rajesh C. Miranda

This study shows that prenatal exposure to both alcohol and cannabinoids in mice reduces fetal cerebral blood flow more than either drug alone and predicts perinatal mortality.

BMC Pregnancy and Childbirth · Apr 11, 2024Peer-reviewedDevelopmental Biology

Maternal Circulating MiRNAs That Predict Infant FASD Outcomes Influence Placental Maturation

Alexander Mike Tseng, Amanda H. Mahnke, Alan Wells, Nihal A. Salem, Andrea M. Allan, Victoria H. J. Roberts, Natali Newman, Nicole A. R. Walter, Christopher D. Kroenke, Kathleen A. Grant, Lisa K. Akison, Karen M. Moritz, Christina Chambers, Rajesh C. Miranda, CIFASD

The paper identifies maternal circulating miRNAs that predict infant FASD outcomes and show they impair placental development by inhibiting the EMT pathway in trophoblasts.

Life Science Alliance · Mar 4, 2019Peer-reviewedDevelopmental Biology