Author

Joseph Ipe

Indiana University IndianapolisORCID 0000-0002-8362-4403Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Hai LiniD· 2 shared Jill L. ReiteriD· 2 shared Katherine A. GallawayiD· 2 shared Todd C. SkaariD· 2 shared Yunlong LiuiD· 2 shared Alison GoateiD· 1 shared Andy B. CheniD· 1 shared D.N. CooperiD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersNeuroscience

Hai LinORCID

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Author profile →

2 papers

Recent·Most cited

Allele-Specific Expression and High-Throughput Reporter Assay Reveal Functional Variants in Human Brains with Alcohol Use Disorders

Xi Rao, Kriti S. Thapa, Andy B. Chen, Hai Lin, Hongyu Gao, Jill L. Reiter, Katherine A. Gallaway, Joseph Ipe, Dongbing Lai, Xiaoling Xuei, Yue Wang, Hongmei Gu, Manav Kapoor, Sean P. Farris, Jay A. Tischfield, , Yunlong Liu

The paper identifies functional variants in human brains with alcohol use disorders by combining allele-specific expression analysis with high-throughput reporter assays.

Molecular Psychiatry · Sep 2, 2019Peer-reviewedNeuroscience

RegSNPs-Intron: A Computational Framework For Prioritizing Intronic Single Nucleotide Variants in Human Genetic Disease

Hai Lin, Katherine A. Gallaway, Rudong Li, Jill L. Reiter, Matthew E. Mort, D.N. Cooper, Yaoqi Zhou, Michael T. Eadon, M. Eileen Dolan, Joseph Ipe, Todd C. Skaar, Yunlong Liu

The paper develops regSNPs-intron, a random forest classifier to prioritize intronic SNVs for disease, validated using ASSET-seq functional assays.

bioRxiv · Jan 9, 2019 · PreprintBioinformatics