Author

Hongmei Gu

Indiana University School of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alison GoateiD· 1 shared Andy B. CheniD· 1 shared Dawei ZhangiD· 1 shared Dongbing LaiiD· 1 shared Hai LiniD· 1 shared Hongyu GaoiD· 1 shared Howard J. EdenbergiD· 1 shared Isha RalhaniD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Alison GoateORCID

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2 papers

Recent·Most cited

ApoE4 impairs astrocyte lipid droplet formation via endolysosomal dysfunction

Isha Ralhan, Ju-Young Bae, Nathanael Y.J. Lee, Wendy Cai, Jinlan Chang, Suha Jarad, Hongmei Gu, Dawei Zhang, Maria S. Ioannou

This study shows ApoE4 impairs astrocyte lipid droplet formation by disrupting endolysosomal function and demonstrates that PCSK9 can restore lipid droplet formation by preventing ApoE4 internalization.

bioRxiv · Sep 4, 2026 · PreprintNeuroscience

Allele-Specific Expression and High-Throughput Reporter Assay Reveal Functional Variants in Human Brains with Alcohol Use Disorders

Xi Rao, Kriti S. Thapa, Andy B. Chen, Hai Lin, Hongyu Gao, Jill L. Reiter, Katherine A. Gallaway, Joseph Ipe, Dongbing Lai, Xiaoling Xuei, Yue Wang, Hongmei Gu, Manav Kapoor, Sean P. Farris, Jay A. Tischfield, , Yunlong Liu

The paper identifies functional variants in human brains with alcohol use disorders by combining allele-specific expression analysis with high-throughput reporter assays.

Molecular Psychiatry · Sep 2, 2019Peer-reviewedNeuroscience