Systematic discovery of receptor-ligand biology by engineered cell entry and single-cell genomics
Bingfei Yu, Quanming Shi, Julia A. Belk, Kathryn E. Yost, Kevin R. Parker, Huang Huang, Daniel Lingwood, Mark M. Davis, Ansuman T. Satpathy, Howard Y. Chang
This paper introduces ENTER-seq, a method using engineered lentiviral particles to systematically discover receptor-ligand interactions and map TCR specificity in single cells.
bioRxiv · Dec 13, 2021 · PreprintGenomics