Kevin R. Parker

This study introduces CRISPRai, a bidirectional epigenetic editing system, to investigate gene regulation hierarchies and interactions in T cells and hematopoietic lineage transcription factors.

The paper identifies Hnrnpa2b1 as a key RBP regulating myogenic differentiation through post-transcriptional control in skeletal muscle regeneration.

This paper introduces ENTER-seq, a method using engineered lentiviral particles to systematically discover receptor-ligand interactions and map TCR specificity in single cells.

The paper predicts SARS-CoV-2 RNA localization to host mitochondria and nucleolus using machine learning, identifying key regions in viral RNA that drive this localization.

Perturb-ATAC combines CRISPR perturbations with single-cell ATAC-seq to identify gene regulatory networks in human cells.

The paper identifies the promoter of ciRS-7 as overlapping with LINC00632 and shows ciRS-7 exonic sequence is embedded in linear transcripts in human and mouse.