Bingfei Yu

This study maps metabolic changes in 12 organs of male and female mice across 5 ages, identifying sex-specific patterns and a metabolic aging clock.

ProVADA adapts proteins to non-native contexts by steering a pretrained generator while preserving function, successfully converting renin and deimmunizing antibodies.

This study shows that Xist ribonucleoprotein complexes drive sex-biased autoimmunity in males, leading to autoimmune pathology and reprogramming of immune cells to resemble female patterns.

This paper introduces ENTER-seq, a method using engineered lentiviral particles to systematically discover receptor-ligand interactions and map TCR specificity in single cells.

This study shows XIST is required in adult human B cells to silence X-linked immune genes and identifies TRIM28 as a B cell-specific XIST cofactor involved in X-inactivation and atypical B cell formation.