Konika Chawla

Pyranges v1 provides a Python framework for efficient sequence interval operations, offering speed and functionality improvements over existing tools like BEDTools.

The paper identifies non-coding RNAs involved in cell cycle regulation by analyzing RNA, RNA polymerase II, and promoter activity changes across the cell cycle in human keratinocytes.

This study shows that SNHG26, a G2-phase enriched lncRNA, is necessary for cell cycle progression and proliferation, with effects on mitochondrial stress and gene expression.