Author

Ioannis Koutroulis

Children's NationalORCID 0000-0002-8396-9022Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:metabolomics· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:imaging· 2

Frequent Co-Authors

Maria TriantafyllouiD· 5 shared Panagiotis KratimenosiD· 5 shared Vittorio GalloiD· 5 shared Gabriele SimontiiD· 4 shared Georgios SanidasiD· 4 shared Javid GhaemmaghamiiD· 4 shared Nora WolffiD· 4 shared Chad E. ByrdiD· 3 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersNeuroscience

Maria TriantafyllouORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Divergent Pontine and Cerebellar Pathology in Preterm Infants With Necrotizing Enterocolitis

Georgios Sanidas, Helen Chen, Gabriele Simonti, Javid Ghaemmaghami, Rodolfo Cardenas, Chad Byrd, Courtney Lowe, Laura Kim, Maria Triantafyllou, Nora Wolff, Robinson Vidva, Anthony Sandler, Billie Lou Short, Tania Siahanidou, Christina Kanaka-Gantenbein, , Panagiotis Kratimenos

This study identifies divergent brain pathology in preterm infants with NEC, showing distinct cellular and molecular changes in the pons and cerebellum.

bioRxiv · Nov 2, 2026 · PreprintNeuroscience

Intrinsic Gestational Timing Governs Human Cerebellar Development After Preterm Birth

Georgios Sanidas, Gabriele Simonti, Javid Ghaemmaghami, Kyla Woyshner, Antonis Polyviou, Robinson Vidva, Courtney Lowe, Abhya Vij, Daniel C. Bittel, Maria Triantafyllou, NICOLAS WOLFF, Rodolfo Cardenas, Helen Chen, Francisco Almeida, Sniya Valsa Sudhakar, , Panagiotis Kratimenos

The paper shows that prematurity disrupts cerebellar development by altering developmental trajectories and causing lineage-specific asynchrony in cell maturation.

Science · Oct 29, 2026Peer-reviewedNeuroscience

Developmental Arrest Associated with Altered Cerebellar Metabolism in Sudden Infant Death Syndrome

Javid Ghaemmaghami, Gabriele Simonti, Georgios Sanidas, Nora Wolff, Maria Triantafyllou, Rodolfo Cardenas Trejo, Henrik Sahlin Pettersen, Vittorio Gallo, Ioannis Koutroulis, Panagiotis Kratimenos

The paper investigates cerebellar dysfunction in SIDS by integrating multi-omic data, finding metabolic and developmental abnormalities linked to neuroinflammation and impaired autonomic responses.

bioRxiv · Jul 21, 2026 · PreprintNeuroscience

Prematurity Insults Remodel Cerebellar Development and Behavior

Georgios Sanidas, Gabriele Simonti, Javid Ghaemmaghami, Kyla Woyshner, Robinson Vidva, Daniel C. Bittel, Nora Wolff, Maria Triantafyllou, Antonis Polyviou, Chad E. Byrd, Courtney Lowe, Henry Salisbury, Evan Z. Goldstein, Aaron Sathyanesan, Ioannis Koutroulis, , Panagiotis Kratimenos

This study models prematurity-associated insults in mice to show how different insults and their sequence alter cerebellar development and lead to distinct behavioral outcomes.

bioRxiv · Jul 22, 2025 · PreprintNeuroscience

Cross-species biomarkers of cerebellar injury in acute sepsis: integrated metabolomics of mouse cerebellum and plasma identify conserved human plasma biomarkers and therapeutic modulation by human MSC-sEVs

Dylan W. Crawford, Maria Triantafyllou, Nora Wolff, Marc Carlson, Chad E. Byrd, David R. M. Graham, Panagiotis Kratimenos, Vittorio Gallo, Ioannis Koutroulis

The paper identifies cross-species plasma biomarkers for septic encephalopathy using metabolomics in mice and humans, and shows therapeutic effects of MSC-sEVs.

bioRxiv · Jun 26, 2025 · PreprintNeuroscience