Javid Ghaemmaghami

This study identifies divergent brain pathology in preterm infants with NEC, showing distinct cellular and molecular changes in the pons and cerebellum.

The paper shows that prematurity disrupts cerebellar development by altering developmental trajectories and causing lineage-specific asynchrony in cell maturation.

The paper investigates cerebellar dysfunction in SIDS by integrating multi-omic data, finding metabolic and developmental abnormalities linked to neuroinflammation and impaired autonomic responses.

CytoSignal detects and quantifies ligand-receptor signaling interactions at cellular resolution from spatial transcriptomic data, enabling spatial gradient analysis and temporal dynamics prediction.

VISTA-FISH links live-cell imaging with gene expression in neurons to study differentiation and cellular activity.

This study models prematurity-associated insults in mice to show how different insults and their sequence alter cerebellar development and lead to distinct behavioral outcomes.