Author

Yaru Xu

Yale UniversityORCID 0000-0002-8397-311XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Ping MuiD· 2 shared Siyuan ChengiD· 2 shared Anfeng Luo· 1 shared Assma AlrefaiiD· 1 shared Catherine Yijia Zhang· 1 shared Ha Eun Shin· 1 shared Isaac Yi KimiD· 1 shared Lin LiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Ping MuORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer LettersPeer-reviewedMar 28, 2026

RUNX1T1-HDAC Reprogramming of the HOX Code Signaling Drives a Targetable Pan-Cancer Lineage Plasticity

Yuyin Jiang, Siyuan Cheng, Catherine Yijia Zhang…·Ping Mu

The paper identifies RUNX1T1 as a marker of lineage plasticity across cancers and shows that targeting the RUNX1T1-HDAC complex can suppress plastic cell growth.

5 citations

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintMar 26, 2025

Androgen Deprivation-Induced TET2 Activation Fuels Prostate Cancer Progression via Epigenetic Priming and Slow-Cycling Cancer Cells

Lin Li, Siyuan Cheng, Yaru Xu…·Xiuping Yu

This study identifies TET2 activation in slow-cycling cells as a driver of prostate cancer progression through epigenetic changes and shows targeting TET2 suppresses tumor growth.

3 citations

humanscRNA-seq

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