STAT3 Sustains Tumorigenicity Following Mutant KRAS Ablation
Stephen D’Amico, Varvara Kirillov, Jingxuan Liu, Zhijuan Qiu, Xinyuan Lei, Hong Qin, Brian S. Sheridan, Nancy C. Reich
This study shows that STAT3 sustains tumorigenicity in KRAS-ablated pancreatic cancer cells, highlighting its role in maintaining malignant identity and suggesting it as a therapeutic target.
EMBO Reports · Aug 26, 2025Peer-reviewedCancer Biology