Author

Carla V. Finkielstein

Carilion ClinicORCID 0000-0002-8417-4643Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

Alessandro CeciiD· 3 shared Ignacio AielloiD· 3 shared Andrew P. Biesemier· 1 shared Anne M. BrowniD· 1 shared Camila Agustina SennaiD· 1 shared Clinton D. RobyiD· 1 shared Daniel G. S. CapellutoiD· 1 shared Diego Andres GolombekiD· 1 shared

Activity by Year

2018-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCell Biology

Alessandro CeciORCID

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4 papers

Recent·Most cited

A temporally regulated miRNA signature in pancreatic cancer extracellular vesicles disrupts the circadian clock and promotes muscle atrophy

jonathan church, Ignacio Aiello, Alessandro Ceci, Goeun jang, Carla V. Finkielstein

bioRxiv · May 4, 2026 · PreprintCell Biology

Circadian Disruption Drives Extracellular Matrix Remodeling to Facilitate Pulmonary Metastatic Colonization

Ignacio Aiello, Guido Hokama, Alessandro Ceci, Camila Agustina Senna, Diego Andres Golombek, Natalia Paladino, Carla V. Finkielstein

This study shows circadian disruption promotes pulmonary metastasis by altering ECM remodeling and YAP/TEAD-driven EMT programs in mice, with similar patterns observed in human melanoma.

bioRxiv · Apr 23, 2026 · PreprintCancer Biology

White-tailed deer milk exhibits SARS-CoV-2 neutralizing antibodies and synergistic mechanisms that contribute to rapid viral RNA degradation

lorena p tobar, W Cantwell Smith, Hannah Raso, Katherine L. Brown, Alessandro Ceci, Matthew G. Urbano, Clinton D. Roby, Dzenis Mahmutovic, Andrew P. Biesemier, Daniel G. S. Capelluto, Ignacio Aiello, Dominic S. Raso, Carla V. Finkielstein

This study identifies SARS-CoV-2 neutralizing antibodies and rapid viral RNA degradation in white-tailed deer milk, revealing distinct antiviral mechanisms compared to human milk.

bioRxiv · Feb 12, 2026 · PreprintMicrobiology

Distinct control of PERIOD2 degradation and circadian rhythms by the oncoprotein MDM2

Jingjing Liu, Xianlin Zou, Tetsuya Gotoh, Anne M. Brown, Liang Jiang, Esther L. Wisdom, Jae Kyoung Kim, Carla V. Finkielstein

This study identifies MDM2 as a regulator of PER2 degradation and shows it influences circadian rhythm period length through a phosphorylation-independent mechanism.

Science Signaling · Nov 13, 2018Peer-reviewedMolecular Biology