Effect of nuclear electrostatic potential on the nucleoplasmic distribution of histones and nucleosome stability
Yuqi Guo, Fei He, Xin Dai, Jiaying Yu, Yixuan Li, Fenfang Li, Cheng‐han Yu, Ying Wai Chan, Andrew W. Holle, Esteban Hoijman, Artem K. Efremov
This study shows that differences in electrostatic potential between heterochromatin and euchromatin affect nucleosome stability and transcription factor access, explaining transcriptional differences.
bioRxiv · Jul 25, 2026 · PreprintBiophysics