Quan Wen

This study shows that activating serotonergic neurons in the dorsal raphe nucleus of zebrafish induces a quiescent state that differs from sleep, specifically affecting motor activity.

The paper identifies coupling correlation as a structural determinant of macroscopic neural dynamics and validates this principle across species using empirical data.

The paper identifies multi-timescale motor dynamics in C. elegans head exploratory behavior using variational mode decomposition and neuronal ablation, revealing roles of specific motor neurons in locomotion.

The paper identifies two novel proteins, EGC-2 and EGC-3, that are essential for E granule assembly and small RNA homeostasis in C. elegans using TurboID-based proximity labeling and RNAi screening.

The paper analyzes whole-brain calcium activity in zebrafish to show scale-invariant neural activity patterns explained by Euclidean Random Matrix theory.

This paper introduces a mesoscopic SCAPE microscope with a super-oblique light sheet and rescanning strategy, achieving high-resolution volumetric imaging over large fields of view.

This study identifies a dual role for SAA interneurons in C. elegans, influencing both short-term rhythmic motor activity and long-term behavioral transitions.

This study identifies a master neuron in C. elegans that modulates forward and backward movement through tonic and phasic activity at different timescales.

The paper introduces an all-optical technique for brain-wide calcium imaging and optogenetic stimulation in larval zebrafish, showing it can trigger behavior and neural activity changes.

The paper shows that juvenile C. elegans generate symmetric motor patterns through an asymmetric motor circuit, with dorsal bending driven by synaptic wiring and ventral bending via extrasynaptic signaling from premotor interneurons.

This study develops a high-throughput operant learning system for larval zebrafish and shows that lower visual intensity ratios enhance learning responses and memory extinction.

The paper investigates how AVB-B gap junctions in C. elegans facilitate undulatory wave propagation during forward locomotion through intrinsic motor neuron oscillations and proprioceptive coupling.

This study develops a technique to image whole brain neural activity in freely behaving larval zebrafish during specific behaviors.