Author

Amanda L. Huff

Johns Hopkins UniversityORCID 0000-0002-8423-8985Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Amanda PoissonnieriD· 1 shared Andrew AdeyiD· 1 shared Christopher CherryiD· 1 shared Dmitrijs LvovsiD· 1 shared Elana Judith FertigiD· 1 shared Elizabeth M. JaffeeiD· 1 shared Jacob T. MitchelliD· 1 shared Jacquelyn W. ZimmermaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Amanda PoissonnierORCID

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1 paper

Recent·Most cited

Differential cell signaling testing for cell-cell communication inference from single-cell data by dominoSignal

Jacob T. Mitchell, Orian Stapleton, Kavita Krishnan, Sushma Nagaraj, Dmitrijs Lvovs, Christopher Cherry, Amanda Poissonnier, Wesley R. Horton, Andrew Adey, Varun Rao, Amanda L. Huff, Jacquelyn W. Zimmerman, Luciane Tsukamoto Kagohara, Neeha Zaidi, Lisa M. Coussens, , Elana Judith Fertig

The paper introduces dominoSignal, a software tool that statistically tests differential cell signaling from single-cell data to infer changes in cell-cell communication networks.

Bioinformatics · Feb 26, 2026Peer-reviewedBioinformatics