Author

Nagraj Mani

Pledge TherapeuticsORCID 0000-0002-8446-2338Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Ali H. MunawariD· 1 shared Asanga BandaraiD· 1 shared Consuelo C. Sierra· 1 shared Cristina Ubeda NicolauiD· 1 shared Erin E. DeansiD· 1 shared Fernando Henrique MartinsiD· 1 shared Miriam Cerrada· 1 shared Onno AkkermansiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Ali H. MunawarORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Natural and patient-derived mutations in BK polyomavirus VP1 reveal structural determinants of BC-loop dependent antibody escape

Onno Akkermans, Cristina Ubeda Nicolau, Asanga Bandara, Consuelo C. Sierra, Fernando Henrique Martins, Steff De Graef, Erin E. Deans, Stephen J. Ross, S. Sienaert, Miriam Cerrada, Vipul Chimanlal Chitalia, Nagraj Mani, S.D. Weeks, Ali H. Munawar

The paper identifies BC-loop mutations in BKPyV VP1 that reduce antibody binding and neutralization, highlighting challenges for therapeutic development.

bioRxiv · Aug 9, 2025 · PreprintMicrobiology