Author

Keiji Saito

Sapporo Medical UniversityORCID 0000-0002-8464-3198Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Atsushi KunoiD· 1 shared Hori Tomoki· 1 shared Iyori Nojima· 1 shared Koki AbeiD· 1 shared Ryo NumazawaiD· 1 shared Ryusuke HosodaiD· 1 shared Tatsuya SatoiD· 1 shared Yuki TatekoshiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperPharmacology & Toxicology

Atsushi KunoORCID

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1 paper

Recent·Most cited

Activation of the NAD⁺-Sirtuin Axis Protects Against Chronic Doxorubicin-Induced Subclinical Renal Tubular Injury Through Restoration of Mitochondrial Homeostasis and Suppression of Inflammation

Keiji Saito, Ryusuke Hosoda, Ryo Numazawa, Hori Tomoki, Iyori Nojima, Yukika Saga, Yuki Tatekoshi, Tatsuya Sato, Koki Abe, Atsushi Kuno

This study shows that chronic low-dose doxorubicin causes mitochondrial dysfunction and inflammation in renal tubules, which can be mitigated by activating the NAD⁺-Sirtuin axis with resveratrol or NMN.

bioRxiv · Aug 3, 2026 · PreprintPharmacology & Toxicology