Koki Abe

This study shows that chronic low-dose doxorubicin causes mitochondrial dysfunction and inflammation in renal tubules, which can be mitigated by activating the NAD⁺-Sirtuin axis with resveratrol or NMN.

This study identifies a muscle-to-bone signaling pathway where CX3CL1 from muscle endothelial cells promotes bone repair via CX3CR1-expressing osteoprogenitors.

This study shows that altered renal vascular patterning reduces ischemic kidney injury and preserves vascular function in aging mice.