Karthik Devarajan

A germline KDM3C polymorphism impairs DNA repair and sensitizes to chemoradiotherapy

The paper identifies a germline KDM3C polymorphism linked to impaired DNA repair and increased sensitivity to chemoradiotherapy in cancers like rectal and head and neck squamous cell carcinomas.

Probability-based methods for outlier detection in replicated high-throughput biological data

The paper develops probability-based methods for detecting outliers in replicated high-throughput biological data and demonstrates their application using experimental and simulated data.

Unified methods for feature selection in large-scale genomics data with censored survival outcomes

The paper introduces methods for feature selection in genomics data with censored survival outcomes, addressing non-proportional hazards and outperforming existing approaches.

Supervised dimension reduction for large-scale \"omics\" data with censored survival outcomes under possible non-proportional hazards

The paper develops supervised methods for feature selection and survival prediction in large-scale omics data with censored outcomes and time-varying effects using continuum power regression and accelerated failure time models.