Chao Wu

The paper identifies a germline KDM3C polymorphism linked to impaired DNA repair and increased sensitivity to chemoradiotherapy in cancers like rectal and head and neck squamous cell carcinomas.

The paper investigates how aging-dependent dysregulation of EXOSC2 affects cellular traits and finds that PPP2R5E, a PP2A phosphatase subunit, is a key target of EXOSC2, with this regulation maintained in stem cells and cancer.

This study shows that SNCA deletion disrupts olfactory sensory neuron projection via the NCK2-EphA4 pathway, contributing to olfactory deficits in synucleinopathies.

This study identifies how ATP drives efficient terpene biosynthesis in marine thraustochytrids by enhancing thermodynamic driving force through energy metabolism shifts.