CAR T-cell and oncolytic virus dynamics and determinants of combination therapy success for glioblastoma
Martina Conte, Agata Xella, Ryan T. Woodall, Kevin A. Cassady, Sergio Branciamore, Christine E. Brown, Russell C. Rockne
This study uses a mathematical model to analyze CAR T-cell and oncolytic virus dynamics in glioblastoma, identifying virus bursting size as a key determinant of combination therapy efficacy.
Mathematical Biosciences · Sep 15, 2025Peer-reviewedImmunology