Author

Kevin A. Cassady

Nationwide Children's HospitalORCID 0000-0003-2474-9051Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexia K. MartiniD· 2 shared Agata XellaiD· 1 shared Ali A. AshkariD· 1 shared Ana L. PortilloiD· 1 shared Beau R. WebberiD· 1 shared Branden S. MoriarityiD· 1 shared Christine E. BrowniD· 1 shared Colin T. MaguireiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

Alexia K. MartinORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologyMathematical BiosciencesPeer-reviewedSep 15, 2025

CAR T-cell and oncolytic virus dynamics and determinants of combination therapy success for glioblastoma

Martina Conte, Agata Xella, Ryan T. Woodall…·Russell C. Rockne

This study uses a mathematical model to analyze CAR T-cell and oncolytic virus dynamics in glioblastoma, identifying virus bursting size as a key determinant of combination therapy efficacy.

11 citationstop 2%

humanstatistical model

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ImmunologybioRxivPreprintAug 30, 2025

Off-the-shelf allogeneic polyclonal CD38KO/CD38-CAR γδT cells for the treatment of T cell malignancies

Genesis Snyder, Alexia K. Martin, Yasemin Sezgin…·Meisam Naeimi Kararoudi

This paper develops CD38KO/CD38-CAR γδT cells for T cell malignancies, showing they effectively target T-ALL without causing fratricide or GvHD.

3 citations

humanproteomics

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ImmunologyJournal for ImmunoTherapy of CancerPeer-reviewedJul 1, 2025

Oncolytic HSV-IL27 expression improves CD8 T cell function and therapeutic activity in syngeneic glioma models

Alexia K. Martin, Jack Hedberg, Ilse Hernandez-Aguirre…·Kevin A. Cassady

This study develops an oncolytic HSV expressing IL-27 (C027) that improves survival in syngeneic glioma models by enhancing CD8 T cell function and inducing durable immune memory.

6 citations

mouseexperimental assay

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