Author

Karen K.L. Mestan

University of California San DiegoORCID 0000-0002-8506-784XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Abhik Chakraborty· 1 shared Abhineet Sharma· 1 shared Benjamin Waked· 1 shared Daniel Kaminsky· 1 shared Debashis SahooiD· 1 shared Gregory Bellan· 1 shared Hannah PalaciD· 1 shared Ilan Gur· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBioinformatics

Abhik Chakraborty

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3 papers

Recent·Most cited

Sparse Machine Learning Pipeline with Stabl Identifies Cord Blood Multi-Omic Signatures of Bronchopulmonary Dysplasia

Karen K.L. Mestan, Janu Newar, Jiaqi Zhao, Abhik Chakraborty, Jonathan D. Reiss, William E. Funk, Ina Annelies Stelzer, Benjamin Waked, Gregory Bellan, Xavier Durand, Julien Jacques Hedou

The paper uses a sparse machine learning pipeline to identify multi-omic biomarkers predictive of bronchopulmonary dysplasia in cord blood samples.

bioRxiv · Sep 18, 2026 · PreprintBioinformatics

Macrophage Polarizations in the Placenta and Lung are Associated with Bronchopulmonary Dysplasia

Karen K.L. Mestan, Abhineet Sharma, Sarah Lazar, Sonalisa Pandey, Mana M. Parast, Louise Chang Laurent, Lawrence S. Prince, Debashis Sahoo

This study investigates the relationship between placental and lung macrophage polarization and their role in the development of bronchopulmonary dysplasia.

bioRxiv · Jan 26, 2024 · PreprintSystems Biology

Vital Signs Analysis Algorithm Detects Inflammatory Response in Premature Infants with Late Onset Sepsis and Necrotizing Enterocolitis

Leena Bhattacharya Mithal, Ram Yogev, Hannah Palac, Daniel Kaminsky, Ilan Gur, Karen K.L. Mestan

The paper evaluates the RALIS algorithm for early detection of late onset sepsis and necrotizing enterocolitis in premature infants using vital signs data.

Early Human Development · Jan 23, 2018Peer-reviewedBioinformatics