Author

Minoru Takaoka

University of CambridgeORCID 0000-0002-8515-8282Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Dirk Paul· 1 shared Fabien LareyreiD· 1 shared James HarrisoniD· 1 shared Leanne Masters· 1 shared Marc ClémentiD· 1 shared Rahul SharmaiD· 1 shared Yuning Lu· 1 shared Ziad MallatiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperPathology

Dirk Paul

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1 paper

Recent·Most cited

Modelling the human IL6RA Asp358Ala variant in mice: effects on atherosclerosis and abdominal aortic aneurysm

Minoru Takaoka, Rahul Sharma, Fabien Lareyre, Marc Clément, James Harrison, Leanne Masters, Yuning Lu, Dirk Paul, Ziad Mallat

This paper shows that introducing the IL6RA Glu357Ala substitution in mice reduces atherosclerosis and AAA, similar to the human IL6RA Asp358Ala variant's protective effect.

bioRxiv · Oct 21, 2026 · PreprintPathology