Pragmatic analysis with knowledge-guided for unraveling peptide-protein pairwise non-covalent mechanisms
Shutao Chen, Ke Yan, Jiangyi Shao, Xiangxiang Zeng, Bin Liu
KGIPA improves prediction of peptide-protein non-covalent interactions by integrating biological knowledge and multimodal features, outperforming existing methods in binding residue and affinity prediction.
bioRxiv · Feb 13, 2026 · PreprintBioinformatics