ImmunologybioRxivPreprint
Crystal structure of activated MAPKAPK2 kinase reveals a C-lobe allosteric pocket for furan-2-carboxamide inhibitors
Edward Beaumont, Stéphanie Duclos, Sandrine Thieffine…·john Barker
The paper determines the crystal structure of activated MAPKAPK2 with a non-ATP-competitive inhibitor, revealing an allosteric binding pocket for drug design.
DOI 10.64898/2026.10.01.755332