Author

Debra J. McAndrew

University of OxfordORCID 0000-0003-2086-1724Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

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Adam Linekar· 1 shared Andreas KoschinskiiD· 1 shared Christopher N. ToepferiD· 1 shared Connor M. BlairiD· 1 shared Craig A. LygateiD· 1 shared Cristina E. MolinaiD· 1 shared David HendersoniD· 1 shared David Revuelta· 1 shared

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1 shared paperCell Biology

Adam Linekar

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintNov 18, 2025

Precision Targeting of Troponin I Phosphorylation Prevents Diastolic Dysfunction while Preserving Systolic Performance

Ying‐Chi Chao, Debra J. McAndrew, David Revuelta…·Manuela Zaccolo

This paper identifies a nanodomain mechanism regulating troponin I phosphorylation and demonstrates a peptide that selectively enhances relaxation without compromising systolic function in heart failure.

DOI 10.1101/2025.11.18.689162

mousehuman

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