Author

Alessandro Bevilacqua

Okinawa Institute of Science and Technology Graduate UniversityORCID 0000-0002-8541-8603Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Assay:imaging· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Mirco DindoiD· 2 shared Paola LaurinoiD· 2 shared Amy Q. SheniD· 1 shared Erika FukuharaiD· 1 shared Jakob MetsoniD· 1 shared Kiyoshi YagiiD· 1 shared Mark V. SullivaniD· 1 shared Mauricio Rios MacieliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Mirco DindoORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedOct 30, 2026

Enzymes can activate and mobilize the cytoplasmic environment across scales

Mirco Dindo, Jakob Metson, Weitong Ren…·Paola Laurino

This study shows that enzymes in biomolecular condensates enhance catalytic activity through crowding-induced conformational changes and enable increased mobility despite environmental viscosity.

8 citations

proteomicsexperimental assay

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BiochemistrybioRxivPreprintSep 28, 2024

Enzyme Activity Regulates Substrate Diffusion by Modulating Viscosity in Crowded Milieu

Alessandro Bevilacqua, Mauricio Rios Maciel, Mark V. Sullivan…·Paola Laurino

This study shows enzymatic activity reduces viscosity in crowded environments, enhancing substrate diffusion by up to three-fold through disruption of non-covalent interactions.

3 citations

imagingexperimental assay

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