Author

M. Amine Hassani

Broad InstituteORCID 0000-0002-8544-4940Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:long-read sequencing· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Jacob E. LemieuxiD· 2 shared Alexander ArvanitisiD· 1 shared Ali A Djarou· 1 shared Allen C. SteereiD· 1 shared Amina Abdalla· 1 shared Ashlee M. EarliD· 1 shared Ben KotzeniD· 1 shared Brandon L. GarciaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

Jacob E. LemieuxORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Heterologous Surface Display Reveals Conserved Complement Inhibition and Functional Diversification of Borrelia burgdorferi Elp Proteins

Nathan Hill, Lara M. Matulina, Cameron MacIntyre, M. Amine Hassani, Sheila Thomas, Matteo Luban, Isabelle Ward, Amina Abdalla, John M. Leong, Brandon L. Garcia, Jacob E. Lemieux

The paper uses E. coli surface display to study Borrelia burgdorferi Elp proteins, revealing their conserved complement inhibition and novel interaction with perlecan.

Molecular Microbiology · May 16, 2025Peer-reviewedMicrobiology

Linkage blocks involving multiple replicons organize Borrelia burgdorferi strain variation and influence virulence in Lyme disease

R Laing, Michael Joshua Foster, M. Amine Hassani, Ben Kotzen, Alexander Arvanitis, Weihua Huang, Terrence Shea, Ali A Djarou, Gordon C. Adams, Stephen F. Schaffner, Tjasa Cerar, Lisa M. Freimark, Eva Ružić‐Sabljić, Dionysios Liveris, Radha Iyer, , Jacob E. Lemieux

This study uses long-read assemblies to show that genetic modules across multiple plasmids organize Borrelia burgdorferi strain variation and influence virulence in Lyme disease.

bioRxiv · Jan 29, 2025 · PreprintMicrobiology