ImmunologybioRxivPreprint
Targeting the APRIL-BAFF axis in IgA nephropathy: preclinical insights from influenza challenge and single-cell spatial profiling
Kirk J. Rowley, Vinay Singh, Anna Roberts…·Luke N. Robinson
This study compares selective APRIL and dual APRIL/BAFF inhibition in mice and humans, finding that dual blockade more severely disrupts B-cell maturation and immune protection.